https://www.cell.com/cell/pdf/S0092-8674(26)00174-1.pdf

“Living” Digital Model of an actual Cell!

ALT

attached is a link to the paper. here’s the tl;dr

These scientists essentially made a “digital twin” of a simple cell. They ran simulations which are meant to mimic it’s brief life down to the genetic level. They found that the simulation matched results from the lab.

Just a few days ago I also posted a story about a digital twin of a fruitfly, where researchers used its connectome (brain connections) embodied in a digital fly in a virtual environment and it successfully generated apparently authentic fly behavior.

We may really be on the cusp of emulating biology, which has two major implications:
1. The really far out implication is that we could theoretically upload our minds after death and live in a virtual environment.

2. On a more grounded level, we may reach a point where we can emulate whole organisms with high fidelity. This would revolutionize biology and medicine. It could see how a particular chemical might interact with every part of the body and help in designing medicines perfectly catered to each person.

These are both huge stories and something to keep an eye on in the years ahead.

“We may have been a bit silly….”

Poggers (2x) combo

🔋💡 Stop Buying New Batteries! Universal Rechargeable Coin Cell Charger with LED

TRACKing the tissue-specific origins of diverse effector T cell functions - Immunology Research

Nature Immunology, Published online: 12 March 2026; doi:10.1038/s41590-026-02475-w
A dual-recombinase fate-mapping system enables the permanent labeling of T cells activated during a treatment window, providing insights into the site-specific acquisition of diverse effector functions acquired at different antigen-priming sites.

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TRACKing the tissue-specific origins of diverse effector T cell functions - Immunology Research

Hidden metabolism found operating inside the cell nucleus

A new study published in Nature Communications has revealed that more than 200 metabolic enzymes can be found directly on human DNA. Many of these enzymes are typically known for producing energy in mitochondria, yet researchers discovered them sitting on chromatin inside the cell nucleus.

The study shows that different cell types, tissues, and cancers each display their own distinctive…

Hidden metabolism found operating inside the cell nucleus

things like PCs are only girls or xyz is only boys because we anthropomorphize them. are we not too, anthropomorphizing ourselves via transgenderism. somethingsomething bigword

Postdoc Portrait: Brandon Reagan’s Research on Plant Cell Stress

Brandon Reagan uses advanced imaging to study how plant cells manage the stress response within the endoplasmic reticulum.
Image credit:©iStock.com, R_Koopmans

Brandon Reagan is a postdoctoral researcher working in the lab of Federica Brandizzi at Michigan State University. He is a plant cell biologist studying how cells respond to stress and how plants establish a balance between growth and…

Postdoc Portrait: Brandon Reagan’s Research on Plant Cell Stress

“…you couldn’t get me on the landline eh? You should’ve tried….”

“…My CELL!!!”

Ghost in the Cell (2026) | Movie | Movies Dock

🎬 Title: Ghost in the Cell / Hantu Dalam Sel
Story: Within the grim walls of Labuan Angsana, one of the most infamous prisons in the country, survival is a day-to-day struggle. Tension runs high as rival gangs clash and corrupt guards reign terror, leaving inmates with little hope. But when a mysterious force starts to eliminate prisoners one after another, chaos erupts within the prison. In a…

Ghost in the Cell (2026) | Movie | Movies Dock

Hypoxia shapes immune cell organization and bacterial control in tuberculosis granulomas - Immunology Research

Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
This is a summary of: McCaffrey, E. F. et al. The immunometabolic topography of cellular organization and bacterial control in tuberculosis granulomas. Nat. Immunol. https://doi.org/10.1038/s41590-026-02431-8 (2026).

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Hypoxia shapes immune cell organization and bacterial control in tuberculosis granulomas - Immunology Research

“Well hello there, Gaston. You ducked out of arm wrestling with me when last we met, despite it being your idea. Are you prepared today?”

“Caught me at a bad time, I’m afraid. I’m saving my arm strength for golfing later on.”

“Heh. Almost sounds to me like an excuse, but sure, I’ll let it go, provided you’re much better prepared whenever next we may meet.”

“If he’s not going to play any strong arming games with you, then might I propose a friendly game of basketball? You against me!”

“Basketball, huh? Such a fast moving, high jumping sport does sound like it would be most enjoyable. But I think I should be able to find better opponents than you.”

“Excuse me, but I’ve a thrust that’s strong enough to knock players clean out when I simply throw the ball right at their heads! I’m the fastest moving player out there at the moment, and I bet I could jump higher than you could ever reach!”

“Your movement speed, if really what you claim, would not surprise or confound me too terribly. But a dwarfish form like your’s was simply not made for high jumps, I’m afraid. You lack the legs for it, and what’s more, you don’t even have anything on your body that could propel you higher. Not even wings!”

“Wings? Oh, you’d better come back here should I call you out at around this time next month, and I’ll show you wings! HOT wings, even!”

“Orders, you guys???”

“Ah. Oh, yes, just an apple juice and a fried egg sandwich for me!”

“Yes, and make mine a sourdough melt with Body Split Cappuccino Potion.”

“No, I do not have thoughts on frogs. Why would I? I don’t have any of Captain Ginyu’s cells in me from what I can recall. Frogs interest me not, so let’s drop this froggy foolishness, shall we?”

“I hear you there, brother! Frogs are just cogs! No use wasting time and energy talking about them!”

Focused ultrasound-enhanced cell therapy for brain tumors: Summary of roundtable discussions - Research

Cell-based immunotherapies have emerged as promising strategies for brain tumors, offering the potential for targeted and durable antitumor responses. However, their efficacy has been limited by challenges unique to the central nervous system, including suboptimal delivery routes and an immunosuppressive tumor microenvironment that impairs cell function. Focused ultrasound (FUS) is a noninvasive…

Focused ultrasound-enhanced cell therapy for brain tumors: Summary of roundtable discussions - Research

“That’d be a negative. I know that there’s at least one that looms large over the City of Villains who possesses far more power than I do, but in terms of fighting strength, stamina, and techniques, I don’t think even they could take me. All other villains I’ve come across have been a mixed lot. I’ve met some that almost equal me, but none who surpass me. Not even the Dark One has that sort of perfect power.”

“Should ever I come upon a villain who claims to exceed me in fighting strength and capabilities, I’d love to see them back up such a claim. And all the more amusing if I can prove them wrong.”

Streamlining T Cell Analysis Using High-Throughput Cytometry

This webinar will be hosted live and available on-demand.
Thursday, April 23rd, 202611:00 AM – 12:00 PM ET
As interest in CAR T cells and immune-based oncology therapies increases, efficient phenotyping of cell therapy products becomes more crucial. Because this process involves analyzing surface markers that characterize cell types, it requires compatible antibodies and interrogation…

Streamlining T Cell Analysis Using High-Throughput Cytometry

isnt this exciting!!!!!??!?!??!?!?

NIR-II Fluorescent Timer-Embedded Drug for Real-Time Tracing of Immunogenic Cell Death and Guiding Chemo-immunotherapy - Research

Immune adjuvants are essential components in chemo-immunotherapy; however, determining the optimal administration timing to synchronize them with recruited immune cells is challenging due to the difficulty in in vivo tracing of immunogenic cell death (ICD). Current ex vivo ICD assessment methodologies delay reporting and are thus incapable of guiding in situ chemo-immunotherapy. Here, we develop…

NIR-II Fluorescent Timer-Embedded Drug for Real-Time Tracing of Immunogenic Cell Death and Guiding Chemo-immunotherapy - Research

Scientists Finally Solve the Mystery of Cell Membrane Behavior - Science News

A long-standing mystery about cell membrane behavior may finally be resolved. Cell membranes are the thin, flexible skins that surround living cells. They protect what is inside, control what gets in and out, and can even shape how a cell behaves. For a long time, though, membranes have also seemed oddly unpredictable. Results from well-known […]

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NIR-II Fluorescent Timer-Embedded Drug for Real-Time Tracing of Immunogenic Cell Death and Guiding Chemo-immunotherapy - Research

Immune adjuvants are essential components in chemo-immunotherapy; however, determining the optimal administration timing to synchronize them with recruited immune cells is challenging due to the difficulty in in vivo tracing of immunogenic cell death (ICD). Current ex vivo ICD assessment methodologies delay reporting and are thus incapable of guiding in situ chemo-immunotherapy. Here, we develop…

NIR-II Fluorescent Timer-Embedded Drug for Real-Time Tracing of Immunogenic Cell Death and Guiding Chemo-immunotherapy - Research